Why We Love NAD+ IV Therapy — Brain, Energy, Longevity and More

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If you’ve ever wished for more energy, sharper focus, or a better way to support aging, NAD+ therapy might be exactly what you’re looking for. At Hyer Health, we offer IV and injection options for NAD+, tailored to your needs — whether you’re recovering from burnout, optimizing brain performance, or supporting long-term cellular health.

What Is NAD+?

NAD+ IV Therapy - total cellular healthNAD+ stands for nicotinamide adenine dinucleotide — a molecule found in every living cell.
It helps your body:

  • Turn food into energy
  • Repair damaged DNA
  • Regulate sleep and circadian rhythm
  • Support brain function and mood
  • Activate longevity genes (sirtuins)
  • Detox harmful substances

As we age or deal with stress, inflammation, or illness, our NAD+ levels naturally decline — which can lead to fatigue, poor focus, slower healing, and signs of aging.

NAD+ IV Therapy vs. Injection: What’s the Difference?

IV NAD+ is ideal for deep cellular support, especially for neurological issues, fatigue, or detox. Infusions are longer (1–2+ hours) and allow for higher doses.

Injections (IM or subcutaneous) are quick and effective for maintenance or milder symptoms, and can be used several times a week.

Many patients start with IV infusions weekly for 4–6 weeks, then switch to monthly infusions or weekly injections for maintenance.

What Are the Benefits of NAD+ Therapy?

  • Increased energy
  • Improved focus and memory
  • Anti-aging and DNA repair
  • Cellular detox and repair
  • Mitochondrial health support
  • Better workout recovery and endurance
  • Mood regulation and reduced anxiety

Off-Label and Research-Based Uses

NAD+ therapy is being explored for a range of conditions:

  • Chronic fatigue syndrome
  • Migraines
  • Neurodegenerative disorders like Alzheimer’s and Parkinson’s
  • Autoimmune diseases and inflammation
  • Addiction recovery
  • Egg and sperm quality for fertility support
  • Anti-aging and longevity medicine

Why We Love It (and Why Athletes Do Too)

NAD+ is one of our favorite regenerative therapies because it doesn’t just mask symptoms — it restores function at the cellular level. Whether you’re a busy parent, a high-performing executive, or a competitive athlete, NAD+ helps your body and brain perform better under pressure and recover faster.

Athletes use NAD+ to:

  • Enhance stamina and strength
  • Reduce post-exercise inflammation
  • Speed up recovery between training sessions

How Often Should You Use It?

Goal Suggested Frequency:

  • Brain fog or fatigue Weekly IV x 4–6, then monthly
  • Longevity / anti-aging Monthly IV or 2–3x/week injections
  • Athletic performance Weekly injection or pre/post event
  • Migraine support Weekly to biweekly depending on severity
  • Fertility/egg quality support Weekly during preconception phase

Precautions

  • Some people may feel a “tight” chest or body sensation during IV NAD+ due to its impact on cellular metabolism. This is normal and we can adjust the infusion rate.
  • Not recommended for pregnant or breastfeeding women.
  • Always discuss other medications and medical conditions with your provider before starting NAD+.

View our full IV Menu and schedule an appointment today!

References

1. Covarrubias AJ, Perrone R, Grozio A, Verdin E. NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol. 2021;22(2):119-141.
2. Martens CR, Denman BA, Mazzo MR, et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nat Commun. 2018;9:1286.
3. Brown KD, Maqsood S, Huang JY, et al. Activation of SIRT3 by the NAD+ precursor nicotinamide riboside protects from noise-induced hearing loss. Cell Metab. 014;20(6):1059-1068.
4. McReynolds MR, Chellappa K, Baur JA. Age-related NAD+ decline. Curr Opin Clin Nutr Metab Care. 2020;23(1):1–10.
5. Yaku K, Okabe K, Nakagawa T. NAD metabolism: Implications in aging and longevity. Ageing Res Rev. 2018;47:1-17.

Methylene Blue IV Therapy — A Mitochondrial Powerhouse with Surprising Benefits

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Methylene blue might sound like a science lab chemical — and in fact, it originally was — but this bright blue compound is now making waves in functional and integrative medicine for its unique ability to support energy, brain health, and longevity. When delivered intravenously, methylene blue offers a range of benefits, especially for those looking to boost mitochondrial function, cognitive performance, and cellular resilience.

Info about Methylene Blue IV Therapy

A Brief History of Methylene Blue

Methylene blue was first synthesized in the 1800s as a textile dye, but by the late 1800s it was being used in medicine to treat malaria — making it one of the earliest synthetic drugs. Over the years, it became an FDA-approved treatment for methemoglobinemia (a condition where red blood cells can’t carry oxygen effectively), and has been studied for its potential in neurodegenerative diseases, infections, and mood disorders.

 

What Is Methylene Blue Used For Today?

  • FDA-Approved Uses:
    • Methemoglobinemia
    • Diagnostic dye in surgeries
  • Off-Label Uses (Often IV or Oral):
    • Cognitive enhancement
    • Fatigue and brain fog
    • Neurodegenerative conditions (Alzheimer’s, Parkinson’s)
    • Post-viral fatigue or long COVID
    • Mitochondrial dysfunction
    • Lyme disease and co-infections
    • Chronic Fatigue Syndrome
    • Depression and anxiety
    • Antiviral and antimicrobial support

Oral vs. IV Methylene Blue

  • Oral:
    • Convenient, lower doses
    • May be helpful for daily mitochondrial support
    • Slower absorption, less predictable bioavailability
  • IV:
    • Higher bioavailability and precision
    • Faster onset and more pronounced effects
    • Better suited for acute brain fog, fatigue, or neurological support

How Methylene Blue Helps Your Cells Make Energy

Inside almost every cell in your body are tiny engines called mitochondria. These engines turn the food you eat and the air you breathe into energy — kind of like a battery charger for your body. When your mitochondria aren’t working well, you can feel tired, foggy, or just not yourself.

Methylene blue helps these little engines run better. It:

  • Gives your cells a shortcut to make energy faster
  • Helps clean up waste and damage inside your cells
  • Keeps your brain and body sharp and strong

This is why it’s often used to help people with low energy, brain fog, or trouble focusing. Some doctors are even exploring it for conditions like memory loss, long COVID, or mood changes.

Research shows that methylene blue can increase cellular oxygen consumption, enhance brain metabolism, and protect neurons from damage, which is why it’s gaining popularity for patients with fatigue, brain fog, and cognitive decline.

Precautions & Contraindications

  • Drug interactions: Methylene blue is a mild MAOI (monoamine oxidase inhibitor), so it may interact with SSRIs, SNRIs, and other antidepressants, potentially leading to serotonin syndrome.
  • Dosing matters: It follows a biphasic dose-response (i.e., more isn’t better). Higher doses can actually reduce its effectiveness.
  • Not suitable for: Pregnant or breastfeeding women, people with G6PD deficiency, or those taking serotonergic psychiatric medications unless cleared.

Final Thoughts

Methylene blue is one of the most fascinating therapies available for mitochondrial health and brain support. When used appropriately — especially in IV form under clinical guidance — it can be a game-changer for patients dealing with neurological issues, chronic fatigue, and cognitive decline.

IV Menu

Experience the ultimate boost in hydration, recovery, and wellness with our premium IV therapy services. IV appointments do not require a Hyer Health membership. Schedule your appointment today using our convenient online scheduler.

View IV Menu and Appointment Scheduling

References

  1. Atamna H, Nguyen A, Schultz C, Boyle K, Newberry J, Kato H. Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways. FASEB J. 2008;22(3):703-712.
  2. Rojas JC, Bruchey AK, Gonzalez-Lima F. Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue. Prog Neurobiol. 2012;96(1):32-45.
  3. Naylor JC, Kilts JD, Hulette CM, et al. Methylene blue reduces abnormal tau protein aggregation in Alzheimer’s disease. Acta Neuropathol Commun. 2020;8(1):134.

 

The Benefits of IV Therapy — Who It’s For & How Often to Use It

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IV therapy has gained popularity in recent years for its ability to deliver vitamins, minerals, and nutrients directly into the bloodstream — offering faster, more effective results than oral supplements. But beyond the hype, IV nutrient therapy has deep clinical roots and can be a powerful tool in optimizing your health when used correctly and consistently.

What Is IV Therapy?

Benefits of IV Therapy

View our IV Menu to learn more about our IV Therapy.

IV (intravenous) therapy bypasses the digestive system, delivering nutrients directly into the bloodstream for maximum absorption. This method ensures that cells receive a concentrated dose of vitamins, minerals, amino acids, antioxidants, and hydration — all essential for optimal function.

Who Can Benefit from IV Therapy?

IV therapy can benefit a wide range of individuals, including those who are:

  • Chronically fatigued or burnt out
  • Experiencing hormonal imbalances
  • Recovering from illness or surgery
  • Managing autoimmune conditions
  • Athletes needing faster recovery
  • Under high levels of stress
  • Struggling with gut absorption issues (e.g., IBS, SIBO, celiac disease)
  • Experiencing frequent migraines or brain fog
  • Interested in anti-aging or longevity support

Even healthy individuals can benefit from IV therapy for immune boosts during flu season, support during travel, or improved skin and hair health.

What Are the Benefits?

Depending on the ingredients used, IV therapy can help:

  • Improve energy and reduce fatigue
  • Strengthen the immune system
  • Enhance mental clarity and mood
  • Support detox pathways and liver health
  • Improve hydration and skin glow
  • Boost athletic performance and recovery
  • Reduce inflammation and oxidative stress
  • Support hormone and adrenal function

How Often Should You Get IV Therapy?

Frequency depends on your health goals and current condition. Here are general guidelines:

GOAL SUGGESTED FREQUENCY
Wellness maintenance 1–2 times per month
Fatigue, stress, or burnout Weekly for 4–6 weeks, then reassess
Athletic performance 1–2 days before/after competition
Detox or recovery 1–2 times weekly depending on labs
Immune boost Monthly or seasonally

 

How do we do it differently for our clients?

We don’t believe in one-size-fits-all.  At Hyer Health, we tailor your IV blends using your symptoms, labs, and even your genetic profile to guide dosing and ingredient selection. This allows us to create a wellness plan that’s truly unique to your body.

IV Menu

Experience the ultimate boost in hydration, recovery, and wellness with our premium IV therapy services. IV appointments do not require a Hyer Health membership. Schedule your appointment today using our convenient online scheduler.

View IV Menu and Appointment Scheduling